~/.config/openbox/lxde-rc.xml
Find the "<keyboard>" section and add the following:
<keybind key="C-A-l">
<action name="Execute">
<command>xscreensaver-command -lock</command>
</action>
</keybind>
~/.config/openbox/lxde-rc.xml
<keybind key="C-A-l">
<action name="Execute">
<command>xscreensaver-command -lock</command>
</action>
</keybind>